Search results for " fusion"
showing 10 items of 1303 documents
Der Zerfall des 2,4-sec100Nb
1972
The nuclide100Nb was produced by irradiation of enriched100Mo targets with 14 MeV-neutrons, and its decay properties were investigated employing scintillation and semiconductor spectrometers and coincidence techniques. A half-life of 2.4±0.3 sec and aQ β-value of 5.8±0.2 MeV were found. From 27 gamma-rays, 20 transitions, representing 95% of the observed gamma-ray intensity, could be placed in a decay scheme comprising 10 excited states of100Mo.
The beta-decay of95Rb and97Rb
1983
Theβ-decay of 377 ms95Rb and 168ms97Rb has been thoroughly investigated by means ofγ-ray, conversion electron andβ-delayed neutron spectroscopy. More than 97% of theβ-decay to particle-bound states has been placed in level schemes of95Sr and97Sr. High-resolution neutron spectroscopic studies have allowed to extend the knowledge of the excitation spectra up to 9 MeV, respectively 10 MeV. The density of neutron-unbound levels in95Sr and97Sr has been derived from peak stripping analyses of the neutron spectra. Beta-strength functions (S β(E)) have been investigated in detail. They indicate that Gamow-Tellerβ-decay of both precursors is dominated by nuclear structure. The discovered pronounced …
In vitro fusion of phagosomes with different endocytic organelles from J774 macrophages.
1998
We describe novel biochemical and electron microscopy assays to investigate in vitro fusion of latex bead phagosomes with three different endocytic organelle fractions from J774 macrophages. After formation, early phagosomes fuse avidly with early and late endosomes and for a longer period of time with lysosomes, but they subsequently become fusion-incompetent. The fusion of early, but not late, phagosomes with all three endocytic fractions could be significantly stimulated by Rab5. In contrast to other cell types investigated, this Rab is uniquely enriched on both early and late endosomes in J774 macrophages. Moreover, exogenous Rab5 stimulates homotypic fusion between both sets of organel…
AN IL-6/IL-6 SOLUBLE RECEPTOR (IL-6R) HYBRID PROTEIN (H-IL-6) INDUCES EPO-INDEPENDENT ERYTHROID DIFFERENTIATION IN HUMAN CD34+CELLS
2000
H-IL-6 is a hybrid protein constructed to contain IL-6 and its soluble receptor linked by a flexible peptide chain. Here we show that H-IL-6 strongly enhances proliferation of human CD34(+)cells in serum-free liquid culture, and that the majority of the cells generated belong to the erythroid lineage, being positive for the marker Glycophorin A. Conversely, H-IL-6 does not increase the number of myeloid, CD13-positive cells. Comparable effects are observed on progenitors from cord blood and adult peripheral blood. Therefore, H-IL-6 triggers an erythroid-inducing signal in haematopoietic progenitor cells, independently from erythropoietin (EPO).
CD38-Specific Biparatopic Heavy Chain Antibodies Display Potent Complement-Dependent Cytotoxicity Against Multiple Myeloma Cells
2018
CD38 is overexpressed by multiple myeloma cells and has emerged as a target for therapeutic antibodies. Nanobodies are soluble single domain antibody fragments derived from the VHH variable domain of heavy chain antibodies naturally occurring in camelids. We previously identified distinct llama nanobodies that recognize three non-overlapping epitopes of the extracellular domain of CD38. Here, we fused these VHH domains to the hinge, CH2, and CH3 domains of human IgG1, yielding highly soluble chimeric llama/human heavy chain antibodies (hcAbs). We analyzed the capacity of these hcAbs to mediate complement-dependent cytotoxicity (CDC) to CD38-expressing human multiple myeloma and Burkitt lymp…
Depth Attention for Scene Understanding
2022
Deep learning models can nowadays teach a machine to realize a number of tasks, even with better precision than human beings. Among all the modules of an intelligent machine, perception is the most essential part without which all other action modules have difficulties in safely and precisely realizing the target task under complex scenes. Conventional perception systems are based on RGB images which provide rich texture information about the 3D scene. However, the quality of RGB images highly depends on environmental factors, which further influence the performance of deep learning models. Therefore, in this thesis, we aim to improve the performance and robustness of RGB models with comple…
Meson exchange and isobar current effects in nuclear photon scattering
1980
Explicit expressions of meson exchange and isobar current contributions to the nuclear two-photon amplitude are derived in the non-relativistic limit. In connection with this amplitude the requirement of gauge invariance on the photon scattering amplitude and on the nuclear electromagnetic interaction operator is discussed in detail.
Radioactive decay of 217Pa
2002
The radioactive decay of 217Pa was investigated by means of α-γ-spectroscopy. Fine structure in the ground-state α-decay was established. Ambiguities in the fine structure of the α-decay of the previously known isomeric state could be clarified by α-γ-coincidence measurements. A previously unknown α-transition of Eα = (8306 ± 5) keV was detected and identified by means of delayed α-α- and α-γ-γ-coincidence measurements. A second isomeric state decaying by α-emission was not observed. The quality of the previously reported data of the α-decay fine structure of 217Th was improved.
Beta Decay of 111Tc to 111Ru
1998
The β-decay of the very neutron-rich 111Tc nucleus has been observed. A partial decay scheme of 111Ru is presented, complementing the high-spin levels earlier reported in spontaneous fission work.
Minimal invasive posterior correction of Lenke 5C idiopathic scoliosis: comparative analysis of minimal invasive vs. open surgery
2019
Introduction Surgical management of adolescent idiopathic scoliosis in spite of usually favourable outcomes is still a major operation. Therefore, efforts are being undertaken to minimalize the procedure, reduce the surgical trauma and postoperative convalescence. The study was designed to compare posterior minimal invasive surgery using navigation based on intraoperative 3D imaging and standard open instrumented fusion in Lenke 5C idiopathic scoliosis treatment. Materials and methods From eight patients with Lenke 5C curves planned for posterior correction and instrumented fusion, four were treated with minimally invasive and four had open procedure. Operation length, estimated blood loss,…